Gestión de conflicto de intereses en investigación y práctica clínica en nutrición

Autores/as

  • Rafael Almendra-Pegueros Laboratorio de Investigación Traslacional en Farmacología, Facultad de Medicia, UASLP https://orcid.org/0000-0002-4411-4515
  • Úrsula Medina Laboratorio de Investigación Traslacional en Farmacología, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México. https://orcid.org/0000-0003-4906-223X

DOI:

https://doi.org/10.35454/rncm.v4nSup.335

Palabras clave:

Conflicto de Intereses, Ética Profesional, Códigos de Ética, Mala Conducta Profesional, Nutricionistas

Resumen

  En el proceso de atención a la salud, la confianza que pacientes, cuidadores y redes de apoyo depositan en el proveedor de salud desempeña un papel importante. Esta confianza puede perderse por la interposición de conflictos de interés (CDI), los cuales se describen como condiciones, en los que el objetivo primario del profesional (atención a la salud o integridad científica) se ve alterado por un objetivo secundario, económico o no.

Descargas

Los datos de descargas todavía no están disponibles.

Biografía del autor/a

Rafael Almendra-Pegueros, Laboratorio de Investigación Traslacional en Farmacología, Facultad de Medicia, UASLP

Licenciado en Nutrición por la Facultad de Nutrición-Veracruz de la Universidad Veracruzana en México. Maestro en Ciencias en Investigación Clínica por la Facultad de Medicina de la Universidad Autónoma de San Luis Potosí en México. Profesor de Asignatura, Universidad Cuauhtémoc-SLP y Universidad del Valle de México SLP. 

Úrsula Medina, Laboratorio de Investigación Traslacional en Farmacología, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México.

Medico Cirujano y Maestra en Ciencias en Investigación Clínica por la Facultad de Medicina de la Universidad Autónoma de San Luis Potosí, México. Doctora en Investigación Biomédica (Farmacología) por la Facultad de Medicina de la Universidad Complutense de Madrid, España. 

Citas

Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: What it is and what it isn’t. BMJ. 1996;312(7023):71-2. doi: 10.1136/bmj.312.7023.71

Birkhäuer J, Gaab J, Kossowsky J, Hasler S, Krummenacher P, Werner C, et al. Trust in the health care professional and health outcome: A meta-analysis. PloS One. 2017;12(2):e0170988. doi: 10.1371/journal.pone.0170988

Hall MA, Dugan E, Zheng B, Mishra AK. Trust in physicians and medical institutions: What is it, can it be measured, and does it matter? Milbank Q. 2001;79(4):613-39. doi: 10.1111/1468-0009.00223

Fineberg HV. Conflict of interest: Why does it matter? JAMA. 2017;317(17):1717-8. doi: 10.1001/jama.2017.1869

Ioannidis JPA, Trepanowski JF. Disclosures in nutrition research: Why it is different. JAMA. 2018;319(6):547-8. doi: 10.1001/jama.2017.18571

Relman AS. The new medical-industrial complex. N Engl J Med. 1980;303(17):963-70. doi: 10.1056/NEJM198010233031703

Relman AS. Dealing with conflicts of interest. N Engl J Med. 1985;313(12):749-51. doi: 10.1056/NEJM198509193131209

Blumenthal D, Gluck M, Louis KS, Wise D. Industrial support of university research in biotechnology. Science. 1986;231(4735):242-6. doi: 10.1126/science.3941897

Thompson DF. Understanding financial conflicts of interest. N Engl J Med. 1993;329(8):573-6. doi: 10.1056/NEJM199308193290812

Royo Bordonada M, García López F. What is and what is not a conflict of interest in public health research. Eur J Public Health. 2018;28(4). doi: 10.1093/eurpub/cky213.750

McKinney RE, Pierce HH. Strategies for addressing a broader definition of conflicts of interest. JAMA. 2017;317(17):1727-8. doi: 10.1001/jama.2017.3857

Bero L. What is in a name? Nonfinancial influences on the outcomes of systematic reviews and guidelines. J Clin Epidemiol. 2014;67(11):1239-41. doi: 10.1016/j.jclinepi.2014.06.015

Bero L. Addressing bias and conflict of interest among biomedical researchers. JAMA. 2017;317(17):1723-4. doi: 10.1001/jama.2017.3854

Bero LA, Grundy Q. Why having a (nonfinancial) interest is not a conflict of interest. PLoS Biol. 2016;14(12):e2001221. doi: 10.1371/journal.pbio.2001221

Saver RS. Is it really all about the money? Reconsidering non-financial interests in medical research. J Law Med Ethics J Am Soc Law Med Ethics. 2012;40(3):467-81. doi: 10.1111/j.1748-720X.2012.00679.x

Burfoot D. Actual and perceived conflicts of interest - Why both matter [Internet]. Independent Broad-based Anti-corruption Commission [consultado el 12 de julio de 2021]. Disponible en: https://www.ibac.vic.gov.au/publications-and-resources/ibac-insights/issue-21/actual-and-perceived-conflicts-of-interest-why-both-matter

Chartres N, Fabbri A, Bero LA. Association of industry sponsorship with outcomes of nutrition studies: A systematic review and meta-analysis. JAMA Intern Med. 2016;176(12):1769-77. doi: 10.1001/jamainternmed.2016.6721

Bes-Rastrollo M, Schulze MB, Ruiz-Canela M, Martinez-Gonzalez MA. Financial conflicts of interest and reporting bias regarding the association between sugar-sweetened beverages and weight gain: A systematic review of systematic reviews. PLoS Med. 2013;10(12):e1001578. doi: 10.1371/journal.pmed.1001578

Bero L, Grundy Q. Conflicts of interest in nutrition research. JAMA. 2018;320(1):93-4. doi: 10.1001/jama.2018.5662

Ludwig DS, Kushi LH, Heymsfield SB. Conflicts of interest in nutrition research. JAMA. 2018;320(1):93. doi: 10.1001/jama.2018.5658

Ioannidis JPA, Trepanowski JF. Conflict of interest in nutrition research - Reply. JAMA. 2018;320(1):94-5. doi: 10.1001/jama.2018.5678

Reinoso Medrano T, Tamarit Díaz T, Pérez Hoz G. La formación de recursos humanos en salud necesarios para el mundo y los paradigmas vigentes. Educ Médica Super. 2012;26(4):635-41

Artaza O, Santacruz J, Girard J, Alvarez D, Barría S, Tetelboin C, et al. Training of human resources for universal health: Strategic actions from academic institutions. Rev Panam Salud Publica. 2020;44:e83. doi: 10.26633/RPSP.2020.83

Caudill TS, Johnson MS, Rich EC, McKinney WP. Physicians, pharmaceutical sales representatives, and the cost of prescribing. Arch Fam Med. 1996;5(4):201-6. doi: 10.1001/archfami.5.4.201

Steinbrook R. Financial support of continuing medical education. JAMA. 2008;299(9):1060-2. doi: 10.1001/jama.299.9.1060

Pizzo PA, Lawley TJ, Rubenstein AH. Role of leaders in fostering meaningful collaborations between academic medical centers and industry while also managing individual and institutional conflicts of interest. JAMA. 2017;317(17):1729-30. doi: 10.1001/jama.2017.2573

Perkmann M, King Z, Pavelin S. Engaging excellence? Effects of faculty quality on university engagement with industry. Res Policy. 2011;40(4):539-52. doi: 10.1016/j.respol.2011.01.007

Catton M. Medical schools tackle conflict of interest. CMAJ Can Med Assoc J. 2005;173(10):1143. doi: 10.1503/cmaj.051295

Wayne DB, Green M, Neilson EG. Teaching medical students about conflicts of interest. JAMA. 2017;317(17):1733-4. doi: 10.1001/jama.2017.2079

Galea S, Saitz R. Funding, institutional conflicts of interest, and schools of public health: Realities and solutions. JAMA. 2017;317(17):1735-6. doi: 10.1001/jama.2017.1659

Cho MK, Shohara R, Schissel A, Rennie D. Policies on faculty conflicts of interest at US universities. JAMA. 2000;284(17):2203-8. doi: 10.1001/jama.284.17.2203

Nestle M. Unsavory truth: How food companies skew the science of what we eat. Estados Unidos: Basic Books. 2018

Kearns CE, Schmidt LA, Glantz SA. Sugar industry and coronary heart disease research: A historical analysis of internal industry documents. JAMA Intern Med. 2016;176(11):1680-5. doi: 10.1001/jamainternmed.2016.5394

Navarrete-Muñoz EM, Tardón A, Romaguera D, Martínez-González MÁ, Vioque J. Food industry funding and epidemiologic research in public health nutrition. Gac Sanit. 2018;32(2):168-71. doi: 10.1016/j.gaceta.2017.04.002

Kroeger CM, Garza C, Lynch CJ, Myers E, Rowe S, Schneeman BO, et al. Scientific rigor and credibility in the nutrition research landscape. Am J Clin Nutr. 2018;107(3):484-94. doi: 10.1093/ajcn/nqx067

Institute of Medicine (US) Committee to Advise the Public Health Service on Clinical Practice Guidelines. Clinical practice guidelines: Directions for a new program. Washington (DC): National Academies Press (US). 1990.

Schmidt M, Lindenauer PK, Fitzgerald JL, Benjamin EM. Forecasting the impact of a clinical practice guideline for perioperative beta-blockers to reduce cardiovascular morbidity and mortality. Arch Intern Med. 2002;162(1):63-9. doi: 10.1001/archinte.162.1.63

Arabi YM, Haddad S, Tamim HM, Al-Dawood A, Al-Qahtani S, Ferayan A, et al. Mortality reduction after implementing a clinical practice guidelines-based management protocol for severe traumatic brain injury. J Crit Care. 2010;25(2):190-5, doi: 10.1016/j.jcrc.2009.05.004

Shiffman RN, Shekelle P, Overhage JM, Slutsky J, Grimshaw J, Deshpande AM. Standardized reporting of clinical practice guidelines: A proposal from the Conference on Guideline Standardization. Ann Intern Med. 2003;139(6):493-8. doi: 10.7326/0003-4819-139-6-200309160-00013

Rosenfeld RM, Shiffman RN. Clinical practice guideline development manual: A quality-driven approach for translating evidence into action. Otolaryngol--Head Neck Surg Off J Am Acad Otolaryngol Head Neck Surg. 2009;140(6):S1-43. doi: 10.1016/j.otohns.2009.04.015

The Lancet null managing conflicts of interests in clinical guidelines. Lancet Lond Engl. 2019;394(10200):710. doi: 10.1016/S0140-6736(19)32000-8

Bindslev JBB, Schroll J, Gøtzsche PC, Lundh A. Underreporting of conflicts of interest in clinical practice guidelines: Cross sectional study. BMC Med Ethics. 2013;14:19. doi: 10.1186/1472-6939-14-19

Tabatabavakili S, Khan R, Scaffidi MA, Gimpaya N, Lightfoot D, Grover SC. Financial conflicts of interest in clinical practice guidelines: A systematic review. Mayo Clin Proc Innov Qual Outcomes. 2021;5(2):466-75. doi: 10.1016/j.mayocpiqo.2020.09.016

Ioannidis JPA. The mass production of redundant, misleading, and conflicted systematic reviews and meta-analyses. Milbank Q. 2016;94(3):485-514, doi: 10.1111/1468-0009.12210

Resnik DB, Konecny B, Kissling GE. Conflict of interest and funding disclosure policies of environmental, occupational, and public health journals. J Occup Environ Med. 2017;59(1):28-33. doi: 10.1097/JOM.0000000000000910

Resnik DB, Elmore SA. Conflict of interest in journal peer review. Toxicol Pathol. 2018;46(2):112-4. doi: 10.1177/0192623318754792

Bosch X, Pericas JM, Hernández C, Doti P. Financial, nonfinancial and editors’ conflicts of interest in high-impact biomedical journals. Eur J Clin Invest. 2013;43(7):660-7. doi: 10.1111/eci.12090

Gottlieb JD, Bressler NM. how should journals handle the conflict of interest of their editors?: Who watches the «watchers»? JAMA. 2017;317(17):1757-8. doi: 10.1001/jama.2017.2207

Liu JJ, Bell CM, Matelski JJ, Detsky AS, Cram P. Payments by US pharmaceutical and medical device manufacturers to US medical journal editors: Retrospective observational study. BMJ. 2017;359:j4619. doi: 10.1136/bmj.j4619

Haque W, Minhajuddin A, Gupta A, Agrawal D. Conflicts of interest of editors of medical journals. PloS One. 2018;13(5):e0197141. doi: 10.1371/journal.pone.0197141

Nestle M. Food company sponsorship of nutrition research and professional activities: a conflict of interest? Public Health Nutr. 2001;4(5):1015-22. doi: 10.1079/phn2001253

Nissen SE. Conflicts of interest and professional medical associations: Progress and remaining challenges. JAMA. 2017;317(17):1737-8. doi: 10.1001/jama.2017.2516

Guzmán-Caro G, García López FJ, Royo-Bordonada MÁ. Conflicts of interest among scientific foundations and societies in the field of childhood nutrition. Gac Sanit. 2021;35(4):320-5. doi: 10.1016/j.gaceta.2020.03.008

Mialon M, Jaramillo Á, Caro P, Flores M, González L, Gutiérrez-Gómez Y, et al. Involvement of the food industry in nutrition conferences in Latin America and the Caribbean. Public Health Nutr. 2021;24(6):1559-65. doi: 10.1017/S1368980020003870

Canella DS, Martins APB, Silva HFR, Passanha A, Lourenço BH. Food and beverage industries’ participation in health scientific events: Considerations on conflicts of interest. Rev Panam Salud Publica. 2015;38(4):339-43.

Larkin I, Ang D, Steinhart J, Chao M, Patterson M, Sah S, et al. Association between academic medical center pharmaceutical detailing policies and physician prescribing. JAMA. 2017;317(17):1785-95. doi: 10.1001/jama.2017.4039

Steinbrook R. Physicians, industry payments for food and beverages, and drug prescribing. JAMA. 2017;317(17):1753-4. doi: 10.1001/jama.2017.2477

DeJong C, Aguilar T, Tseng CW, Lin GA, Boscardin WJ, Dudley RA. Pharmaceutical industry-sponsored meals and physician prescribing patterns for Medicare beneficiaries. JAMA Intern Med. 2016;176(8):1114-22. doi: 10.1001/jamainternmed.2016.2765

Lo B, Grady D. Payments to physicians: Does the amount of money make a difference? JAMA. 2017;317(17):1719-20, doi: 10.1001/jama.2017.1872

College of Dietitian of Alberta Code of Ethics. 1ª edición. Alberta, Canadá: College of Dietitian of Alberta. 2008.

Sah S, Fugh-Berman A. Physicians under the influence: Social psychology and industry marketing strategies. J Am Soc Law Med Ethics. 2013;41(3):665-72. doi: 10.1111/jlme.12076

Goldberg DS. The shadows of sunlight: Why disclosure should not be a priority in addressing conflicts of interest. Public Health Ethics. 2019;12(2):202-12. doi: 10.1093/phe/phy016

Barquera S, García-Chávez CG, Navarro-Rosenblatt D, Uauy R, Pérez-Escamilla R, Martorell R, et al. Postura de la Sociedad Latinoamericana de Nutrición (SLAN) sobre el manejo de conflicto de intereses. Salud Púb Méx. 2018;60(5):592-7. doi: 10.21149/9657

Almendra-Pegueros R, Lozano-Lorca M, Benítez-Brito N, Valera-Gran D, Fernández-Villa T, Soares P, et al. Declaración de conflictos de interés de los editores de la Revista Española de Nutrición Humana y Dietética 2020-2022. Rev Esp Nutr Humana Dietética. 2020;24(3):187-9. doi: 10.14306/renhyd.24.3.1123

Soares MJ, Müller MJ, Boeing H, Maffeis C, Misra A, Muscogiuri G, et al. Conflict of interest in nutrition research: An editorial perspective. Eur J Clin Nutr. 2019;73(9):1213-5. doi: 10.1038/s41430-019-0488-8

Barquera S, Balderas N, Rodríguez E, Kaufer-Horwitz M, Perichart O, Rivera-Dommarco JA, et al. Nutricia code: nutrition and conflict of interest in academia. Salud Púb Méx. 2020;62(3):313-8. doi: 10.21149/11291

Descargas

Publicado

2021-08-05

Cómo citar

Almendra-Pegueros, R., & Medina, Úrsula. (2021). Gestión de conflicto de intereses en investigación y práctica clínica en nutrición. Revista De Nutrición Clínica Y Metabolismo, 4. https://doi.org/10.35454/rncm.v4nSup.335

Artículos más leídos del mismo autor/a